FATTY LIVER AND CROSSTALK

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This blog is for those who have:

  • Fatty liver
  • Type 2 diabetes
  • Metabolic syndrome
  • Some other chronic liver disease, including non-alcoholic fatty liver disease(NAFLD) and non-alcoholic steatohepatitis (NASH)

Crosstalk in medicine means that the colon and its bacterial content are speaking to the liver. And the conversation is anything but good. Bad things are happening. You really want to stop it. Now, for some back round.

The bacteria residing in everyone’s colon should provide many health benefits, if, and only if, the right bacteria are present and in the right proportions. In the colon there are over 1000 species and simply an astounding total number of bacteria present. The bacterial makeup can shift from the good ones to the bad ones. When this happens, these bad bacteria induce a change in the colon wall. The cells lining the wall weaken and allow bacteria and their contents to easily slip through. This is called a leaky bowel. One other nasty thing occurs. Along with a leaky bowel there is low-grade inflammation.
Both of these things are undesirable.

All the blood that leaves the colon goes directly to the liver. From there it is then passed on into the general circulation. So, the liver acts as a gateway to filter out any bad material that occasionally might be coming from the intestine. After all, you do not want any bacterial products to be let loose into your general blood stream. So, along with its many other functions, the liver does this filtering process and it does it very effectively.

However, when there is a leaky bowel along with inflammation, a huge among of these bacterial materials can leach through the colon wall and reach the liver. The liver is overwhelmed and cannot handle it. A fatty liver ensues. This, in turn, can set up a smoldering inflammatory process which causes fibrous tissue to form. This, in turn, damages the liver and leads to cirrhosis, a very serious outcome. It also causes insulin resistance, which leads to and worsens type 2 diabetes.

The way to correct this is to change the bacterial make-up of the colon from the bad bacteria to the good ones. When this happens, the bowel wall begins to heal. Bacterial materials do not leave the colon. There is no longer crosstalk between the colon and the liver. The liver has a chance to recover These facts are well summarized in the current reference below.

TREATMENT

The only way to change the bacterial content of the colon from the bad to the good ones is with diet, specifically a diet that contains a large amount of soluble dietary fibers. The standard Westernize diet is very high in red meat and other animal products. It is also very low in fiber, especially the soluble fibers in plants. These are exactly the plant fibers that the good bacteria use to grow and reproduce. When this happens, the bad bacteria are pushed into the back round. Prebiotic soluble fibers are the ones with the most research behind them. Our product, Prebiotin, is 100% prebiotic soluble fiber and, taken daily, can provide much or most of the soluble fiber your body needs. So, go to our High Fiber Diet for full details on this treatment for Fatty Liver. And don’t forget our Prebiotin Prebiotic Fiber to jump start your program.

Reference

http://www.ncbi.nlm.nih.gov/pubmed?term=role%20of%20innate%20immunity%20and%20the%20microbiota%20in%20liver%20fibrosis

— written by Frank W. Jackson, MD

Jackson GI