Crohn's Disease Dietary Therapy

Hou JK, et al.
Am J Gastroenterol 2011 Apr;106(4):563-73.
Conclusions: High dietary intakes of total fats, PUFAs (polyunsaturated fatty acids), omega-6 fatty acids, and meat were associated with an increased risk of CD (Crohn’s Disease) and UC (Ulcerative Colitis).  High fiber and fruit intakes were associated with decreased CD risk, and high vegetable intake was associated with decreased UC risk.

Swidskinski A, et al.
Inflamm Bowel Dis 2009 Mar; 15(3):359-64.
Conclusions: The emulsifier carboxy methyl cellulose (CMC) induces bacterial overgrowth and small bowel inflammation in susceptible animals.  Because of its ubiquity in products and its unrestricted use in food of the industrial world, CMC is an ideal suspect to account for the rise of IBD (inflammatory bowel disease) in the 20th century.

Roberts CL, et al.
Gut, 2010 Oct;59(10):1331-9 Epub 2010 Sep 2
Conclusions: Translocation of E coli (bacteria) across M-cells (intestinal mucous cells) is reduced by soluble plant fibres, such as inulin and oligofructose (Prebiotin), particularly plantain (bananas) and broccoli, but increased by the emulsifier Polysorbate-80.  These effects occur at relevant concentrations (meaning concentrations that are used in the typical prepared foods) and may contribute to the impact of dietary factors or Crohn’s disease pathogenesis.